But Mr. Cuomo, a third-term Democrat, showed no inclination to heed their call.
In a video rebuttal, Mr. Cuomo disputed the attorney general’s findings and disparaged her aims. He said, as he has in the past, that he has “never touched anyone inappropriately or made inappropriate sexual advances.”
It is not clear how tenable Mr. Cuomo’s hold on power remains. He appears to have few allies left that are not in his employ. Eric Adams, the Democratic nominee for mayor of New York City on whom Mr. Cuomo has lavished praise in recent weeks, called for Mr. Cuomo’s impeachment.
Understand the Scandals Challenging Gov. Cuomo’s Leadership
“Attorney General James conducted a thorough and revealing investigation that yielded disturbing conclusions about the conduct of Governor Cuomo,” he said in a statement. “It is now the duty of the New York State Assembly to take swift and appropriate action and move forward with impeachment proceedings if the governor will not resign.”
Other leading Democrats were even more forceful.
Senators Kirsten Gillibrand and Mr. Schumer, who had called for Mr. Cuomo to step down in March and again on Tuesday, said, “The people of New York deserve better leadership in the governor’s office.”
Carl E. Heastie, the State Assembly speaker, said the report’s findings were “disturbing” and added that “the conduct by the governor outlined in this report would indicate someone who is not fit for office.”
Andrea Stewart-Cousins, the majority leader of the State Senate, repeated her call for Mr. Cuomo’s departure, as did Mayor Bill de Blasio, who has frequently butted heads with Mr. Cuomo.
Mr. de Blasio said on CNN on Tuesday evening that Mr. Cuomo should resign or be impeached “as quickly as possible.” Asked if criminal charges should be considered, the mayor said, “it looks that way to me,” and pointed to the investigation in Albany County.
“My heart goes out to these women,” he said. “They were put through hell by a powerful man.”